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Table 3 Determination of trimebutine maleate in pharmaceutical formulations by the proposed UV-spectrophotometric methods

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

Parameter (claimed concentration of TM)Found %a ± SD
DWD2RDCC-SS
20 μg/mLGast-reg tablets 100 mg (Batch No. 144695)
95.02 ± 0.8393.68 ± 0.5295.11 ± 0.4497.07 ± 0.76
Gast-reg® tablets 200 mg (Batch No. 162912)
96.60 ± 0.4291.47 ± 0.6599.87 ± 0.3198.12 ± 0.50
Gast-reg® ampoules 50 mg/5 mL (Batch No. 154535)
93.04 ± 0.95100.71 ± 0.3095.47 ± 1.2198.48 ± 1.01
24 μg/mLGast-reg® suspension 24 mg/5 mL (Batch No. 163650)
91.53 ± 0.87100.78 ± 0.1294.99 ± 0.5497.72 ± 0.80
  1. aAverage of three determinations