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Table 3 Determination of trimebutine maleate in pharmaceutical formulations by the proposed UV-spectrophotometric methods

From: Different aspects in manipulating overlapped spectra used for the analysis of trimebutine maleate and structure elucidation of its degradation products

Parameter (claimed concentration of TM)

Found %a ± SD

DW

D2

RD

CC-SS

20 μg/mL

Gast-reg tablets 100 mg (Batch No. 144695)

95.02 ± 0.83

93.68 ± 0.52

95.11 ± 0.44

97.07 ± 0.76

Gast-reg® tablets 200 mg (Batch No. 162912)

96.60 ± 0.42

91.47 ± 0.65

99.87 ± 0.31

98.12 ± 0.50

Gast-reg® ampoules 50 mg/5 mL (Batch No. 154535)

93.04 ± 0.95

100.71 ± 0.30

95.47 ± 1.21

98.48 ± 1.01

24 μg/mL

Gast-reg® suspension 24 mg/5 mL (Batch No. 163650)

91.53 ± 0.87

100.78 ± 0.12

94.99 ± 0.54

97.72 ± 0.80

  1. aAverage of three determinations