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Table 1 Effect of MP (150 mg/kg) on ECG pattern in ISO-intoxicated rats

From: Putative anti-inflammatory, antioxidant, and anti-apoptotic roles of the natural tissue guardian methyl palmitate against isoproterenol-induced myocardial injury in rats

Groups

T wave inverted rats (%)

HR (bpm)

QT (s)

QTc (s)

QRS (s)

Control

0 (0%)b

335 ± 31b

0.042 ± 0.01b

0.11 ± 0.023b

0.019 ± 0.002b

MP (150 mg/kg)

0 (0%)b

341 ± 69b

0.044 ± 0.007b

0.13 ± 0.029 b

0.028 ± 0.004b

ISO

8 (80%)a

458 ± 20a

0.1 ± 0.02a

0.3 ± 0.055a

0.05 ± 0.01a

MP (150 mg/kg) + ISO

1 (10%)b

344 ± 21b

0.051 ± 0.012b

0.15 ± 0.013b

0.031 ± 0.006b

  1. Rats were pretreated with MP (150 mg/kg, p.o) three times per week at alternating days for 2 weeks and then 2 consecutive doses of ISO separated by 24 h (85 mg/kg, s.c) on the 13th and 14th days; data are expressed as mean ± SD (n = 10), except for T wave inversions which are indicated as %
  2. a, bSignificantly different from control or ISO groups respectively at P < 0.05 using one-way ANOVA followed by Tukey as a post hoc test