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Table 3 Effect of STV, DTZ, and their combinations on electrocardiographic parameters in isoproterenol-induced myocardial infarction

From: Evaluation of cardioprotection and bio-efficacy enhancement of stevioside and diltiazem in rats

Treatment Heart rate RR (ms) QRS (ms) QT (ms) PR (ms)
Normal control 191.64 ± 7.39 187.96 ± 4.43 137.26 ± 3.31 196.51 ± 3.34 62.85 ± 4.59
ISO control 298.52 ± 10.83*** 288.74 ± 4.26*** 183.52 ± 2.98*** 263.39 ± 3.65*** 113.70 ± 3.89***
DTZ 238.48 ± 7.15***### 254.8 ± 2.64***### 162.20 ± 1.56***## 220.86 ± 2.38***### 85.23 ± 2.11**###
STV 100 268.59 ± 14.73***### 261.83 ± 1.48***### 162.91 ± 2.97***## 234.06 ± 1.79***### 94.95 ± 1.11***##
STV 200 242.10 ± 9.47***### 253.45 ± 3.08***### 164.46 ± 2.92***## 218.12 ± 2.00**### 84.73 ± 1.15**###
STV 100+ DTZ 227.29 ± 4.38***### 249.40 ± 0.83***### 157.60 ± 1.35***### 220.24 ± 4.06**### 85.58 ± 2.78**###
STV 200 + DTZ 211.53 ± 5.96###οο 237.56 ± 1.78*###ο 146.47 ± 3.38###ο 199.73 ± 3.34###οο 68.70 ± 3.72###ο
  1. Results are expressed as mean ± SEM, n = 8
  2. *P < 0.05
  3. **P < 0.01
  4. ***P < 0.001 when compared to normal
  5. ##P < 0.01
  6. ###P < 0.001 when compared to ISO control
  7. οP < 0.05
  8. οοP < 0.01 when compared to DTZ