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Future Journal of Pharmaceutical Sciences

Table 4 Results of the recovery studies using standard addition method

From: Novel approaches for determination of antiretroviral reverse transcriptase inhibitor agent in commercial dosage forms by using spectrofluorimetric, first derivative spectrophotometric, and HPLC methods

Method I

Method II

Method III

Cdrug (μg/mL)

Cadd (μg/mL)

Cdet* (μg/mL)

%Recovery ±SD

%RSD

Cdrug (μg/mL)

Cadd (μg/mL)

Cdet* (μg/mL)

%Recovery ±SD

%RSD

Cdrug (μg/mL)

Cadd (μg/mL)

Cdet* (μg/mL)

%Recovery ±SD

%RSD

5.42

1.57

7.01

101.31 ± 2.74

2.70

12.00

2

14.02

100.06 ± 1.11

0.89

27.09

30

57.64

101.85 ± 0.71

0.70

3.18

8.64

101.24 ± 0.53

0.52

4

15.96

99.25 ± 0.93

1.00

40

65.16

95.18 ± 2.43

2.55

4.76

10.16

99.61 ± 0.73

0.74

6

17.99

97.82 ± 1.08

0.99

50

75.58

96.98 ± 1.38

1.42

6.30

11.98

104.13 ± 1.25

1.20

8

20.10

98.91 ± 0.88

1.11

60

85.10

96.69 ± 1.26

1.31

7.87

13.22

99.04 ± 2.25

2.27

10

22.08

99.04 ± 0.99

1.26

70

95.91

98.32 ± 1.39

1.41

  1. Cdrug drug concentration, Cadd added concentration, Cdet detected concentration, SD standard deviation, RSD relative standard deviation
  2. *Mean concentration of three determinations
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