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Table 2 Composition of topotecan liposome formulation

From: Fabrication and characterization of sterically stabilized liposomes of topotecan

Ingredients

Labeled amount

in mg/mL

Topotecan

1.00

MPEG 2000-DSPE

Sodium salt (Lipoid)

3.19

HSPC (Lipoid S PC-3)

9.58

Cholesterol

3.19

Sucrose

100

Ammonium phosphate*

-

Water for injection

q.s to 1 mL

  1. *Used to create ammonium gradient and removed during processing with traces remaining