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Future Journal of Pharmaceutical Sciences

Table 3 Time recorded for paralysis and death of earthworms for flowered extract of B. nigra and standard drug

From: Exploration of in vitro thrombolytic, anthelminthic, cytotoxic and in vivo anxiolytic potentials with phytochemical screening of flowers of Brassica nigra

Sample

Concentration (mg/ml)

Time (min)

Paralysis time

Death time

Standard (albendazaole)

10

35.40 ± 0.51

73.40 ± 1.21

20

20.80 ± 1.28

54.00 ± 1.45

CSF

10

17.80 ± .58***

30.80 ± 1.11***

20

11.80 ± 1.02**

22.00 ± 1.00***

ASF

10

87.60 ± 0.51***

99.40 ± 0.81***

20

54.40 ± 1.29***

67.60 ± 2.42**

MCE

10

53.60 ± 0.81***

62.20 ± 0.97**

20

33.80 ± 1.24**

47.40 ± 1.57**

n-HSF

10

13.20 ± 0.58***

22.40 ± 1.36***

20

8.80 ± 0.97**

15.60 ± 1.08***

Control (1% CMC in normal saline)

–

–

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  1. Each value represents the mean ± SEM (n = 5)
  2. MCE methanol crude extract, EASF ethyl acetate soluble fraction, n-HSF n-hexane soluble fraction, CSF chloroform soluble fraction, SEM standard error mean
  3. The inter group significance was analysed by one-way ANOVA using Dunnet’s t-test. P < 0.05*, P < 0.01** and P < 0.001*** indicates weak, moderate and high significance respectively
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