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Table 1 Accuracy studies of dolutegravir for developed analytical method

From: Spectrophotometric quantification of dolutegravir based on redox reaction with Fe3+/1,10-phenanthroline

Drug name (brnad name)

Recovery

level %

Amount Taken (μg/mL) (A)

Amt of drug spiked (μg/mL) (B)

Total amount of drug

(μg/mL)

(A + B)

Total amt of drug founda (μg/mL)

Amt of drug recoveredb (μg/mL)

%Amt recovered

%RSDc

Dolutegravir (Tivicay)

80

50.00

40.00

90.00

89.73

39.73

99.3

0.69

100

50.00

50.00

100.00

100.80

50.80

101.6

0.74

120

50.00

60.00

110.00

112.00

62.00

103.3

0.72

  1. aMean of three determinations
  2. bMean of three determinations calculated with respect to amount of drug spiked (B)
  3. cPercentage relative standard deviation