Exploration of anti-breast cancer effects of Terminalia chebula extract on DMBA-induced mammary carcinoma in Sprague Dawley rats

Future Journal of Pharmaceutical Sciences

Table 2 Effect of ethanolic extract of T. chebula on tumor parameters

Group	Tumor volume (mm³)	Tumor weight (mg)	Tumor burden (n)^*	Tumor incidence (%)
Group I	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b	0.00 ± 0.00^b
Group II	0.83 ± 0.07^a	122.7 ± 3.01^a	7.83 ± 0.75^a	6.00 ± 0.89^a
Group III	0.27 ± 0.07^ab	34.00 ± 2.36^ab	3.83 ± 0.75^ab	2.66 ± 0.51^ab
Group IV	0.47 ± 0.12^ab	66.00 ± 2.36^ab	5.00 ± 0.89^ab	5.00 ± 0.89^ab
Group V	0.44 ± 0.01^ab	54.67 ± 2.58^ab	4.66 ± 1.36^ab	4.83 ± 0.75^ab

*n denotes an average number of tumors per animal; values are expressed as mean ± S.D
Statistical significance (p) was calculated by one-way ANOVA followed by Tukey’s multiple comparison tests
The control group was compared with normal; standard and test groups were compared with control; P < 0.05 considered significant