Table 5 Results of the application of proposed methods for Brintellix® tablets
Sample no. | Amount found, mg | ||
|---|---|---|---|
RP-HPLC | Derivative spectrophotometry | ||
237.7 nm | 257.2 nm | ||
1 | 10.07 | 9.51 | 10.26 |
2 | 10.00 | 9.51 | 10.26 |
3 | 10.23 | 9.51 | 9.91 |
4 | 9.87 | 9.73 | 10.26 |
5 | 10.11 | 9.51 | 10.62 |
Mean value*, mg | 10.06 | 9.55 | 10.26 |
Labeled amount, mg | 10.00 | 10.00 | 10.00 |
p: 0,05 C.L, | 10.06 ± 0.16 | 9.55 ± 0.18 | 10.26 ± 0.32 |
RSD | 1.33 | 1.52 | 2.45 |