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Table 5 In vitro release kinetic parameters of metformin from the microspheres

From: Formulation and development of metformin-loaded microspheres using Khaya senegalensis (Meliaceae) gum as co-polymer

Formulation code

Zero order

First order

Higuchi

Korsmeyer-Peppas

 

r2

K

r2

K

r2

k

r2

k

n

FA

0.9594

32.85

0.8308

0.11

0.9552

171.47

0.9970

1.53

0.928

FB

0.9736

43.70

0.8657

0.13

0.9389

189.65

0.9990

1.70

1.210

FC

0.9417

44.11

0.8553

0.11

0.9538

232.20

0.9994

1.50

1.020