Table 7 Comparative study of pharmacokinetic parameters
Parameters | Developed pharmacokinetic method | Previous pharmacokinetic method [7] | ||
|---|---|---|---|---|
CLD | VAL | CLD | VAL | |
Cmax (ng/mL) | 338 ± 13.85 | 1282.21 ± 39.23 | 8.3 ± 4.5 | 4612.6 ± 2302.4 |
Tmax (h) | 3.0 ± 0.81 | 4.0 ± 0.89 | 2.5 | 4 |
AUClast (ng h/mL) | 1069.04 ± 36.93 | 5132.8 ± 76.76 | 38.7 ± 19.7 | 25,864.5 ± 12,611 |
AUC0-∞ ( ng h/mL) | 1117.84 ± 54.90 | 5584.89 ± 125.7 | 43.1 ± 22.5 | 27,498.1 ± 13,676 |