From: Determination of enantiomer impurity in Bortezomib lyo injection formulation by using normal-phase liquid chromatography
(1S,2R-enantiomer) impurity
% Level
% Recovery
% Mean recovery
% RSD
LOQ
85.6
85.9
2.0
87.8
84.4
50%
101.4
101.3
1.7
99.6
103
100%
104.3
105.8
1.8
105.2
108
150%
103.5
1.4
103.3
106