Fig. 5From: Emerging era of microneedle array for pharmaceutical and biomedical applications: recent advances and toxicological perspectivesThe investigational skin of four subjects in which the SC is desquamated. ATRA-MNs applied to the lesion site of each subject for 6 h once per week for 4 weeks. The investigational skin is observed every week. Each image shows the ICDRG score and the presence of desquamation (taken with permission from [130]. Copyright© 2016 Elsevier Inc.)Back to article page