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Table 3 IC50 (μg/ml) values of F. religiosa latex extracts on human cancer cell lines exhibiting best activity

From: Evaluation of chemo-preventive efficacy of Ficus religiosa latex extract by flow cytometry analysis and gene expression studies performed by RT-PCR in various cell lines

S. no Cell lines Ficus religiosa latex extracts IC50 (μg/ml)
1. MDA MB 231 Ethanol 50.86 ± 0.9*
Methanol 145.5 ± 4.5
Acetone 111.86 ± 1.56
Ethyl acetate 107.25 ± 4.12
Doxorubicin 0.82 ± 0.13
2. IMR 32 Ethanol 4.8 ± 1.13*
Methanol 146.01 ± 1.7
Acetone 102.84 ± 0.9
Ethyl acetate 39.24 ± 3.21*
Doxorubicin 0.37 ± 0.05
3. HCT 116 Ethanol 24.27 ± 0.66*
Methanol 122.89 ± 4.01
Acetone 120.71 ± 3.01
Ethyl acetate 101.65 ± 1.6
Doxorubicin 0.48 ± 0.3
  1. Each value is the average of three analyses ± standard deviation of 3 separate experiments in three selected cancer cell lines.
  2. *The IC50 values of the extract in comparison with control drug among all the cell lines were statistically significant (p < 0.001; t test).