From: Determination of residual solvents in paclitaxel by headspace gas chromatography
Solvent | Class | Limit (ppm) |
---|---|---|
Acetone | 3 | 5000 |
Isopropyl alcohol | 3 | 5000 |
Methanol | 2 | 3000 |
Ethanol | 3 | 5000 |
Dichloromethane | 2 | 600 |
n-Hexane | 2 | 290 |
Ethylacetate | 3 | 5000 |
Tetrahydrofuran | 2 | 720 |
N,N-diisopropyl ethylamine | 1 | 20 |