Table 3 Optimized headspace conditions
From: Determination of residual solvents in paclitaxel by headspace gas chromatography
System parameter | Optimum conditions |
|---|---|
Oven temperature | 90 °C |
Loop temperature | 100 °C |
Transfer line temperature | 110 °C |
GC cycle time | 40 min |
Vial equilibration time | 30 min |
Vial pressurization time | 0.5 min |
Loop fill time | 0.5 min |
Loop equilibration time | 0.05 min |
Injection time | 1.0 min |
Vial agitation | Low |