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Table 2 Particle size and flowability properties of RES-NC-DPI and RES-DPI (mean ± SD, n = 3)

From: Fabrication and application of dimyristoyl phosphatidylcholine biomaterial-based nanocochleates dry powder inhaler for controlled release resveratrol delivery

Formulation Particle size (μm) Bulk density Tapped density Angle of repose (θ) Carr’s index Hausner ratio Percent porosity
RES-NC-DPI 102.21 ± 9.83** 0.083 ± 0.01 0.085 ± 0.02 31.72 ± 2.12* 21.17 ± 4.11* 0.97 ± 0.01 42 ± 2.14
RES-DPI 132.33 ± 10.78 0.14 ± 0.04      
0.24 ± 0.12 29.33 ± 3.44 16.24 ± 3.16 0.58 ± 0.21 3 ± 1.11    
RES alone 3.34 ± 1.88  
Respitose® (ML001) 126.88 ± 11.43  
  1. All the determinations are performed in triplicate, and values are expressed as the mean data are mean ± SD (n = 3);
  2. *p ≤ 0.1 (not statistical significant), **p ≤ 0.01 (statistical significant) when compared to the control group RES-DPI