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Table 2 Particle size and flowability properties of RES-NC-DPI and RES-DPI (mean ± SD, n = 3)

From: Fabrication and application of dimyristoyl phosphatidylcholine biomaterial-based nanocochleates dry powder inhaler for controlled release resveratrol delivery

Formulation

Particle size (μm)

Bulk density

Tapped density

Angle of repose (θ)

Carr’s index

Hausner ratio

Percent porosity

RES-NC-DPI

102.21 ± 9.83**

0.083 ± 0.01

0.085 ± 0.02

31.72 ± 2.12*

21.17 ± 4.11*

0.97 ± 0.01

42 ± 2.14

RES-DPI

132.33 ± 10.78

0.14 ± 0.04

     

0.24 ± 0.12

29.33 ± 3.44

16.24 ± 3.16

0.58 ± 0.21

3 ± 1.11

   

RES alone

3.34 ± 1.88

 

Respitose® (ML001)

126.88 ± 11.43

 
  1. All the determinations are performed in triplicate, and values are expressed as the mean data are mean ± SD (n = 3);
  2. *p ≤ 0.1 (not statistical significant), **p ≤ 0.01 (statistical significant) when compared to the control group RES-DPI