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Table 1 Independent variables and levels of experimental design

From: Development, optimization and characterization of flurbiprofen matrix transdermal drug delivery system using Box–Behnken statistical design

S.No.

Independent variables

Code level

Low (− 1)

Mid (0)

High (+ 1)

1.

A = polymer (HPMC K15M: ERL100) ratio

1:1

2:1

3:1

2.

B = concentration of di-butyl phthalate (% w/w)

20

30

40

3.

C = concentration of d-limonene (% w/w)

2.5

05

7.5