From: Development, optimization and characterization of flurbiprofen matrix transdermal drug delivery system using Box–Behnken statistical design
S.No.
Independent variables
Code level
Low (− 1)
Mid (0)
High (+ 1)
1.
A = polymer (HPMC K15M: ERL100) ratio
1:1
2:1
3:1
2.
B = concentration of di-butyl phthalate (% w/w)
20
30
40
3.
C = concentration of d-limonene (% w/w)
2.5
05
7.5