Table 2 Test design and results of response surface analysis

1

FBPT1

3:1

40

5

3.067 ± 0.234

387.99 ± 5.054

7256.7 ± 7.593

1.293 × 10⁻² ± 0.214

3.650

2

FBPT2

3:1

20

5

3.317 ± 0.129

378.07 ± 7.102

7166.16 ± 2.494

1.260 × 10⁻² ± 0.136

3.557

3

FBPT3

2:1

20

2.5

2.570 ± 0.037

313.16 ± 4.872

5475.3 ± 4.289

1.043 × 10⁻² ± 0.089

2.946

4

FBPT4

2:1

40

7.5

2.348 ± 0.021

434.32 ± 9.762

7856.05 ± 6.888

1.447 × 10⁻² ± 0.307

4.086

5

FBPT5

1:1

30

2.5

2.216 ± 0.210

296.45 ± 6.412

5286.44 ± 8.539

0.988 × 10⁻² ± 0.075

2.789

6

FBPT6

2:1

30

5

1.958 ± 0.110

392.67 ± 3.017

7190.05 ± 5.998

1.308 × 10⁻² ± 0.432

3.694

7

FBPT7

3:1

30

7.5

2.783 ± 0.312

468.97 ± 8.294

8543.17 ± 1.939

1.563 × 10⁻² ± 0.065

4.412

8

FBPT8

1:1

40

5

2.489 ± 0.109

351.95 ± 2.829

6485.15 ± 3.228

1.173 × 10⁻² ± 0.245

3.311

9

FBPT9

1:1

20

5

2.230 ± 0.299

336.73 ± 4.210

6165.20 ± 9.298

1.112 × 10⁻² ± 0.121

3.168

10

FBPT10

1:1

30

7.5

2.279 ± 0.023

380.73 ± 10.989

6943.41 ± 4.328

1.269 × 10⁻² ± 0.092

3.582

11

FBPT11

2:1

20

7.5

2.016 ± 0.205

423.91 ± 7.503

7797.18 ± 3.293

1.413 × 10⁻² ± 0.342

3.988

12

FBPT12

2:1

30

5

2.184 ± 0.319

394.11 ± 3.456

6931.19 ± 6.674

1.313 × 10⁻² ± 0.043

3.708

13

FBPT13

2:1

30

5

2.078 ± 0.461

401.63 ± 11.229

6535.14 ± 2.738

1.338 × 10⁻² ± 0.099

3.778

14

FBPT14

2:1

30

5

2.117 ± 0.120

388.67 ± 6.820

6912.86 ± 7.547

1.295 × 10⁻² ± 0.032

3.657

15

FBPT15

3:1

30

2.5

3.128 ± 0.009

326.46 ± 12.482

6085.77 ± 6.837

1.088 × 10⁻² ± 0.164

3.071

16

FBPT16

2:1

40

2.5

2.036 ± 0.223

318.78 ± 8.421

5579.17 ± 10.378

1.062 × 10⁻² ± 0.204

2.999

17

FBPT17

2:1

30

5

2.117 ± 0.199

376.93 ± 5.999

6793.44 ± 5.253

1.256 × 10⁻² ± 0.254

3.546