Table 5 Summary of validation parameters for proposed investigation

 Range (μg/mL)

 Determination coefficient (r²)

0.995

0.996

 Mean percent recovery (%)

99.19–100.05

99.21–100.01

 RSD %

00.20–0.72

0.10–0.83

 Intra-day precision (RSD %)

0.26–1.64

0.10–1.15

 Inter-day precision (RSD %)

0.35–0.44

0.40–0.68

 Repeatability (RSD %)

0.57

0.71

 LOD (μg)

0.10

0.25

 LOQ (μg

0.32

0.45

Robustness

 Analysts-I (mean ± SD)

99.24 ± 0.14

99.45 ± 0.19

 Analysts-II (mean ± SD)

99.95 ± 0.25

99.69 ± 0.27

Specificity

% Assay of drugs

99.78 ± 0.24

99.50 ± 0.17