Future Journal of Pharmaceutical Sciences

Table 4 Arrhenius plot and activation parameters of bedaquiline in different pH solutions

From: Evaluation of physicochemical stability and degradation kinetics of bedaquiline in hydrolytic solutions of different pH

Acid	Activation	r	Ea (kJ/mol)	∆H^↕	∆S^↕
0.1N	ln k= −500.4x−1.181	0.98	4.16	6.43	−54.93
1.0N	ln k= −457.3x−1.007	0.90	3.80	6.07	−53.62
2.0N	ln k= −400.1x−1.196	0.94	3.33	5.60	−51.89
Alkali	Activation	r	Ea (kJ/mol)	∆H^↕	∆S^↕
0.1N	ln k = −424.5x−1.430	0.99	3.52	2.274	−39.71
1.0N	ln k = −337.0x−1.601	0.99	2.80	2.273	−39.71
2.0N	ln k = −336.8x−1.293	0.96	2.80	2.273	−39.71

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