Design and optimization of nano invasomal gel of Glibenclamide and Atenolol combination: in vitro and in vivo evaluation

Future Journal of Pharmaceutical Sciences

Table 4 Summary of results of regression analysis for responses Y1, Y2, and Y3 for fitting to quadratic model

Quadratic model	Sequential p value	Lack of fit F value	Lack of fit p value	Adjusted R²	Predicted R²
Response (Y1)	0.0049	0.2261	0.2261	0.9279	0.8847
Response (Y2)	0.0124	0.2785	0.8391	0.9151	0.8494
Response (Y3)	0.0008	0.3828	0.7719	0.9872	0.9733
Response (Y4)	0.0054	1.92	0.2684	0.9418	0.7433