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Table 4 Summary of results of regression analysis for responses Y1, Y2, and Y3 for fitting to quadratic model

From: Design and optimization of nano invasomal gel of Glibenclamide and Atenolol combination: in vitro and in vivo evaluation

Quadratic model Sequential p value Lack of fit F value Lack of fit p value Adjusted R2 Predicted R2
Response (Y1) 0.0049 0.2261 0.2261 0.9279 0.8847
Response (Y2) 0.0124 0.2785 0.8391 0.9151 0.8494
Response (Y3) 0.0008 0.3828 0.7719 0.9872 0.9733
Response (Y4) 0.0054 1.92 0.2684 0.9418 0.7433