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Table 5 Linearity study of ipratropium bromide and xylometazoline HCl

From: Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

Conc in PPM

Area/response

Ipratropium bromide

 4.01

42839

 50.06

609125

 100.12

1207745

 120.14

1442510

 150.18

1827612

 Slope

12141.8865

 Intercept

−2623.8690

 Correlation coefficient [R]

0.9998

R2

0.9997

Xylometazoline HCl

 4.83

152656

 60.410

1945610

 120.820

3830972

 144.984

4657793

 181.230

5750777

 Slope

31795.0970

 Intercept

9982.2155

 Correlation coefficient [R]

0.9999

R2

0.9999