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Table 5 Linearity study of ipratropium bromide and xylometazoline HCl

From: Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form

Conc in PPM Area/response
Ipratropium bromide
 4.01 42839
 50.06 609125
 100.12 1207745
 120.14 1442510
 150.18 1827612
 Slope 12141.8865
 Intercept −2623.8690
 Correlation coefficient [R] 0.9998
R2 0.9997
Xylometazoline HCl
 4.83 152656
 60.410 1945610
 120.820 3830972
 144.984 4657793
 181.230 5750777
 Slope 31795.0970
 Intercept 9982.2155
 Correlation coefficient [R] 0.9999
R2 0.9999