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Table 11 LOD and LOQ study of Tezacaftor and Ivacaftor in mobile phase and human plasma

From: A rapid RP-HPLC method for the simultaneous estimation of Ivacaftor and Tezacaftor and in silico study of their metabolitic products

Name of the drug

Mobile phase

Human plasma

LOD(μg/mL)

LOQ(μg/mL)

LOD(μg/mL)

LOQ(μg/mL)

Tezacaftor

0.011

0.03

0.09

0.275

Ivacaftor

0.115

0.349

0.31

0.96