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Table 1 Variables for optimization with its upper and lower values (qualitative)

From: Multivariate optimization and evaluation of quaternary mixture in bulk and co-formulated dosage forms by central composite design

S.No

Variable

Variable name

Units

Low value

High value

1

X1

Organic phase

%

30

70

2

X2

Buffer (pH)

Number

4

6

3

X3

Flow rate

ml/min

0.6

1