Table 6 Accelerated stability studies data at 40 °C/75% RH
Time (months) | Particle size (nm) | PDI | Zeta potential (mV) | Saturation solubility(μg/ml) | %CDR10 |
|---|---|---|---|---|---|
0 | 308.18 ± 1.56 | 0.20 ± 0..4 | 26.69 ± 1.56 | 87.78 ± 3.27 | 87.50 ± 1.17 |
1 | 311.33 ± 9.02 | 0.18 ± 0.06 | 25.47 ± 1.24 | 85.36 ± 0.86 | 85.33 ± 0.90 |
3 | 303.67 ± 8.02 | 0.26 ± 0.07 | 24.68 ± 0.96 | 84.20 ± 0.83 | 86.41 ± 1.11 |
6 | 314.33 ± 5.51 | 0.29 ± 0.04 | 27.39 ± 1.17 | 87.75 ± 0.44 | 85.34 ± 1.75 |