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Future Journal of Pharmaceutical Sciences

Table 1 Formulation composition of double-layer drug-in-adhesive formulation

From: The effect of combination of functional and nonfunctional acrylic polymers on transdermal patches of : in vitro permeation, in vivo evaluation using biochemical parameters, and stability studies

Double-layer device total component (%, w/w)

Formulation number

Carvedilol*

Cetyl alcohol*

Ethyl acetate: Span 80*

Durotak 4098*

Durotak 2510*

Duro-Tak 2051*

S 1

6

2

8

42

42

..

S 2

6

2

8

42

..

42

S 3

6

2

8

84

..

..

S 4

6

2

8

..

84

..

S 5

6

2

8

..

..

84

The material composition of a skin contact layer (first) of double-layer TDDS

Skin contact layer

3

2

8

87

..

..

  1. *% w/w of polymer concentration
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