Table 2 Phytochemical constituents of the species

Annona cherimola

Leave, Stem, Seed

kaempferol, quercetin, nicotinflorin , rutin, caffeic acid, Aromin-A; squamocin, Cherimolin, dihydrocherimolin, molvizarin, motrilin, itrabin, jetein, cherimolin-2, almunequin, acetogenins, anomolin, annocherimolin

[33,34,35]

Annona squamosa

Leaves, tender stem, Bark, Seeds, Stem bark.

Anonaine,Anolobine,Aporphine,Corydine,Isocorydine,Norcorydine,Norisocorydine, Glaucine,Liriodenine,Norlaureline,Norushinsunine,Reticuline,Roemerine,Samoquasine A,Annosqualine,Cyclosqamosin A, Cyclosqamosin B, Cyclosqamosin C, Cyclosqamosin D, Cyclosqamosin E, Cyclosqamosin F, Cyclosqamosin G, Cyclosqamosin H, Cyclosqamosin I, Squamtin A, Annosquamosin A, Annonacin, AnnonacinA, Annonastatin, Squamocin, Squamocin-O1, Squamocin-O2, Bullatacin, Bullatacinone, 4-deoxyannoreticuin, cis-4-deoxyannoreticuin(2,4-cis and trans)-squamoxinone, (2,4-cis and trans)-Mosinone A, Mosin B, Mosin C, Squamotacin, Molvizarin, (2,4-cis and trans)-squamolinone, (2,4-cis and trans)-9-oxoasimicinone, Bullacin B, Squamostatin D, (2,4-cis-and trans)-bullatacinone, Squamostatin C, Annonin I, Annonin VI, Squamostene-A, Reticulacin-1, Squamosinin-A, Annotemoyin-1, Annotemoyin-2, Annomosin A, Annosquamosins A,Annosquamosins B, Annosquamosin C, Annosquamosin D, Annosquamosin E, Annosquamosin F, Annosquamosin G.

[36]

Annona macroprophyllata

Seeds

Laherradurin; rolliniastin-2; cherimolin-2

[37]

Annona muricata

Annonaine, nornuciferine, asimilobine, epomusenin-A, epomusenin-B, epomurinin-A, epomurinin-B, cis-annoreticuin, muricin J, muricin K, muricin L, cinnamic acid derivative, coumaric acid hexose, 5-caffeoylquinic acid, dihydrokaempferol-hexoside, p-coumaric acid, caffeic acid derivative, e, dicaffeoylquinic acid, feruloylglycoside, 4-feruloyl-5-caffeoylquinic acid, p-coumaric acid methyl ester, annomuricin A, annomuricin B, annomuricin C, annomuricin E, annomutacin, (2,4-cis)-10R-annonacin-A-one, (2,4-trans)-10R-annonacin-A-one, annohexocin, muricapentocin, (2,4-cis)-isoannonacin, (2,4-trans)-isoannonacin, muricatocin A, muricatocin B, muricatocin C, gigantetronenin,annopentocin A, annopentocin B,annopentocin C, cisannomuricin-D-one, trans-annomuricin-D-one,murihexocin A, murihexocin B, murihexocin C ,muricoreacin, Cis-corossolone, annocatalin, annocatacin B, anonaine, isolaureline, xylopine,Quercetin 3-O-α-rhamnosyl- (1→6)-βsophoroside, gallic acid,epicatechine, quercetin 3-O-rutinosid, quercetin 3-O, neohispredoside, quercetin 3-O-robinoside, catechine, chlorogenic acid, argentinine (1-N,N-dimethylethanyl-4,6-dimethoxy-3,8-dihydroxy-phenanthrene), kaempferol 3-O-rutinoside, quercetin 3-O-glucoside, quercetin, kaempferol, annonamine, (S)-norcorydine, (R)-4′-O-methylcoclaurine

(R)-O,O-dimethylcoclaurine, ,annoionol A, annoionol B, annoionol C, annoionoside,, vomifoliol, roseoside,turpinionoside A,citroside A, blumenol C, (+)-epiloliolide, loliolide, ,rutin, kaempferol 3-O-rutinoside, kaempferol 3-O-robinobioside, kaempferol 3-O-β-D-(2′′-O-β-d-glucopyranosyl,6′′-O-α-L-rhamnopyranosylglucopyranoside, montecristin, cohibin A, cohibin B, cis-solamin, cis-panatellin,cis-uvariamicin IV, cis-uvariamicin I, cis-reticulatacin, cis-reticulatacin-10-one, chatenaytrienin 1, chatenaytrienin 2, chatenaytrienin 3, muridienin 3, muridienin 4, muricadienin, coronin, sabadelin, murisolin, muricatacin, donhexocin, cohibin C, cohibin D, muricatenol, 2,4-cis-gigantetrocinone, 2,4-trans-gigantetrocinone, 2,4-trans-isoannonacin-10-one, annomontacin, longifolicin,muricin A, muricin B, muricin C, muricin D,muricin E,muricin F, muricin G, muricin H, muricin I, cis-annomontacin, annonacinone, xylomaticin, N-fatty acyl tryptamines, annoreticuin-9-one, epoxymurin A

epoxymurin B, corepoxylone, annonacin-10-one, isoannonacin, isoannonacin-10-one,goniothalamicin, gigantetrocin, gigantetrocin A

gigantetrocin B, muricatetrocin A, muricatetrocin B,epomuricenin A

epomuricenin B, annomuricatin A, annocatacin A, annomuricatin C, annonacin

[38]

Annona reticulata

Leaf, Bark, Stem bark, Root, Root bark, Seed, Fruit

Dopamine, Salsolinol, Coclaurine, Sesquiterpenes mainly Spathenelol, Muurolene, Copaene, Eudesmol, Acetogenin – Squamone, Solamin, Annomonicin, Rolliniastatin 2, Annoreticuin-9-one. Triterpenoid – annonaretin A, Monotetrahydrofuron acetogenins, Reticulatacin, Diterpenes: (–)- kau-M-en-19-oiac cid acid and methyl 1β, 17-dihydro-(–)-kauran-19-oate, Alkaloids: Liriodenine, Copaene, Patchoulane and 1H-cycloprop (e) azulene, (-)Kau-16-en-19-oic acid, Bistetrahydrofurone acetogenin, Bullatacin.Dopamine, Salsolinol, Coclaurine, Diterpenes (–)-kaur-16-en-19-oic acid, 16-α-hydroxy-(–)-kauran-19-oic acid, Methyl-17-hydroxy-16-β-(–)-kauran-19-oate, Reticullacinone, Rolliniastatin-2 (=bulatacin = annonin-VI), Molvizarin.Aporphine alkaloids Liriodenine, Norushinsunine, Reticuline, Acetogenin neoannonin, Sesquiterpenes mainly Spathenelol, Muurolene, Copaene, Eudesmol, Anonaine, Michelalbine, Oxoushinsunine, Reticuline, Unknown phenolic comp, Series of N-fatty acyl tryptamine where acyl portion ranged from hexadecanoyl to hexacosanoyl. Cytotoxic acetogenins as Squamocin, cis-/trans-isomurisolenin, Annoreticuin, Annoreticuin-9-one, Bullatacin, cis-/trans-bullatacinone, cis-/trans-murisalinone, Solamin, Annomonicin, Rolliniastatin-1, 2 squamone and isoannonareticin. Volatile oil constituents like α-pinene, β-pinene, Myrcene, Limonene, Terpinen-4-ol, and Germacrene D. Cycloreticulin A, Cycloreticulin B, Acetogenins mainly cis and transisomurisolenin, Annoreticuin, Bullatacin, Squamosine and Rolliniastatin. Aminoacyl triesters of Squamocin 1, N-fatty acyl tryptamines. Annonaceous acetogenins (polykelides): Annonareticin, 2,-4-cis-isoannonareticin, 2, 4-trans-isoannonareticin, Solamin, Murisolin, Reticulacinone, Annoreticuin, Annomonicin, Sitosterol, Daucosterol, Sucrose, Palmitic acid and Stearic acid. Annonaceous acetogenin: 2, 4-cis-isoan-nonareticin,Pinene, Myrcene, Limonene, Terpinen-4-ol, Germacrene D.

[19, 39]

Annona crassiflora

Not reported

–

Annona coriacea

Leaves

Palmitic acid, oleic acid, asitrocinone, annonacin, trilobalicin, annomuricin E, asimicin, bullatacin, annohexocin, murihexocin, goniotriocin, bullatalicinone, annoglaucin, ginsenoside Rh5, salzmanolin, annoheptocin A, annoheptocin B, squamocin glycosilated

[40]

Annona carcans

–

Not reported

Annona cornifolia

Seeds

9-Hydroxyfolianain, annofolin, folianin B, 4-desoxylongimicin, folianin A, squamocin M, squamocin L

[41]

Annona senegalensis

Seed, Root, Leaves

Annosenegalin, Annogalene; gigantetronenine; squamocine; glaucanisine; glaucanetine; goniothalamicine, Roemerine; anonaine; nornuciferine; liriodenine; coclaurine; isoboldine

[42,43,44,45,46]