Scientific name | Parts | Result | Method | References |
---|---|---|---|---|
Annona cherimola | Leaves | Aqueous extract at 300 mg/kg displayed substantial decrease the level of glucose in blood. | Alloxan induced male albinos Sprague-Dawley rats. | |
Juice, Skin, Flesh | Flesh extract at 98.085 Trolox Equivalents per 100 g dose showed maximum scavenging activity. | Oxygen radical absorbance capacity (ORAC) assay | [60] | |
Annona squamosa | Leaves | Aqueous leaf extract revealed significant Antihyperglycemic effect | Streptozotocin-nicotinamide type 2 diabetic rats (250 and 500 mg/kg) | [61] |
 | • IC50 = 40 μg/ml • IC50 = 60 μg/ml • IC50 = 110 μg/ml • IC50 = 115 μg/ml | • ABTS • Nitric oxide • DPPH • Superoxide | [62] | |
Annona macroprophyllata | Leave | With a low IC50 (1.18 μg/ml) repressed the activity of yeast alpha-glucosidase and reduce blood glucose level. | Streptozotocin induced diabetic male Wistar rats. | [63] |
Annona muricata | Leaves | The aqueous extract showed significant blood glucose lowering effect at dose 100 and 200 mg/kg. | Streptozotocin induced diabetic albino Wistar rats. | [64] |
Leaves | Ethanol extract of Annona muricata showed significant antioxidant activity in in vitro model. | DPPH, ABTS, nitric oxide, super oxide, hydroxy radical and lipid peroxidation | [65] | |
Annona reticulata | Leaves | Ethyl acetate fraction from hydroalcoholic extract of Annona reticulata at dose 100 mg/kg reduced blood glucose level significantly. | Streptozotocin induced hyperglycemic Wistar albino rats | [66] |
– | Antioxidant activity not reported. | – | – | |
Annona crassifora | Peel, Seeds, Pulp | Ethanol and aqueous extract express in vitro antioxidant potential. | DPPH and lipid peroxidation assay. | [67] |
– | Not reported Antidiabetic activity. | – | – | |
Annona coriacea | Seeds, Pulp | • DPPH and beta carotene bleaching test showed free radical scavenging activity of 31.53%, 51.59% respectively in in vitro model. | DPPH, Beta-carotene bleaching and ABTS radical cation. | [68] |
Annona carcans | Pulp, Seeds, Leaves | Potent in vitro antioxidant activity was shown by pulp, leaves and seeds extract and fractions. | DPPH, ABTS, and beta-carotene/linoleic acid methods. | [21] |
– | Antidiabetic activity not reported. | – |  | |
Annona senegalensis | Leaves | Aqueous leave extract showed potent antioxidant activity in in vitro model | DPPH, H2O2, superoxide ion, ABTS and ferric ion models | [69] |
– | Antidiabetic activity not reported. | – |  |