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Table 2 Drug designed to treat idiopathic pulmonary fibrosis

From: A review on importance of bioactive compounds of medicinal plants in treating idiopathic pulmonary fibrosis (special emphasis on isoquinoline alkaloids)

S. no. Type/effect Drug used Reference
1 Corticosteroids Cochrane [54]
2 Immunomodulator agent Azathioprine [55]
3 Cytokine inhibitor Etanercept [56]
4 Cytokine Interferon-γ [57]
5 Phosphodiesterase inhibitor Sildenafil [58]
6 Endothelin receptor antagonist Bosentan, macitentan and ambrisentan [59,60,61]
7 Anti-oxidant N-Acetylcysteine [62]
8 Anticoagulant Warfarin or heparin [63]
9 Tyrosine kinase inhibitor Imatinib [64]
10 Tyrosine kinase inhibitor Nintedanib [65]
11 anti-inflammatory, anti-oxidant and anti-fibrotic Pirfenidone [66]
12 Immunosuppressant Cyclosporine A [67]
13 Immunosuppressant Tacrolimus [68]