A review on importance of bioactive compounds of medicinal plants in treating idiopathic pulmonary fibrosis (special emphasis on isoquinoline alkaloids)

Future Journal of Pharmaceutical Sciences

Table 2 Drug designed to treat idiopathic pulmonary fibrosis

S. no.	Type/effect	Drug used	Reference
1	Corticosteroids	Cochrane	[54]
2	Immunomodulator agent	Azathioprine	[55]
3	Cytokine inhibitor	Etanercept	[56]
4	Cytokine	Interferon-γ	[57]
5	Phosphodiesterase inhibitor	Sildenafil	[58]
6	Endothelin receptor antagonist	Bosentan, macitentan and ambrisentan	[59,60,61]
7	Anti-oxidant	N-Acetylcysteine	[62]
8	Anticoagulant	Warfarin or heparin	[63]
9	Tyrosine kinase inhibitor	Imatinib	[64]
10	Tyrosine kinase inhibitor	Nintedanib	[65]
11	anti-inflammatory, anti-oxidant and anti-fibrotic	Pirfenidone	[66]
12	Immunosuppressant	Cyclosporine A	[67]
13	Immunosuppressant	Tacrolimus	[68]