Table 10 ANOVA analysis for trospium chloride ER tablets DOE batches
Response | Source | Sum of squares | df | Mean square | F value | p value | Remarks |
|---|---|---|---|---|---|---|---|
Percent drug release at 2 h (acid stage) | Model | 2027.00 | 7 | 289.57 | 62.76 | < 0.0001 | significant |
Residual | 50.75 | 11 | 4.61 | ||||
Cor Total | 2212.95 | 19 | |||||
Percent drug release at 5 h (Buffer stage) | Model | 3980.94 | 7 | 568.71 | 79.95 | < 0.0001 | significant |
Residual | 78.25 | 11 | 7.11 | ||||
Cor Total | 4267.20 | 19 | |||||
Percent drug release at 11 h (Buffer stage) | Model | 2317.00 | 8 | 289.63 | 66.20 | < 0.0001 | significant |
Residual | 43.75 | 10 | 4.37 | ||||
Cor Total | 2405.75 | 19 | |||||
Percent drug release at 20 h (Buffer stage) | Model | 137.06 | 9 | 15.23 | 25.50 | < 0.0001 | significant |
Residual | 5.37 | 9 | 0.5972 | ||||
Cor Total | 142.55 | 19 |