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Table 1 Management of skin cancer

From: Skin cancer therapeutics: nano-drug delivery vectors—present and beyond

Type of cancer

Type of surgery

Medicines applied topically

Medicines given orally


Basal cell carcinoma

Mohs micrographic surgery (MMS)

Imiquimod, Ingenol mebutate


Radiation therapy, PDT

Squamous cell carcinoma

Standard excision, Mohs micrographic surgery, Curettage and electrodesiccation, Cryosurgery

Imiquimoid, Diclofenac gel (3%), 5-Fluorouracil, Cetuximab

PDT Radiotherapy


Surgical excision, sentinel lymph node biopsy


BRAF kinase Inhibitors-vemurafenib and dabrafenib, encorfenib; NRAS Inhibitors- Binimetinib; cKIT Inhibitors- imitinib and nilotinib and MEK Inhibitors—trametinib and cobimetinib. Immunotherapies for melanoma include Cytotoxic T-lymphocyte Antigen 4 Inhibitors—Ipilimumab; Programmed Cell Death Receptor 1 Inhibitors—Pembrolizumab and Nivolumab and anti-PDL1 (programmed death ligand 1)-Atezolizumab. If these fail Temozolomide and Dacarbazine

Radiation therapy