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Table 1 Management of skin cancer

From: Skin cancer therapeutics: nano-drug delivery vectors—present and beyond

Type of cancer Type of surgery Medicines applied topically Medicines given orally Others
Basal cell carcinoma Mohs micrographic surgery (MMS) Imiquimod, Ingenol mebutate Vismodegib Radiation therapy, PDT
Squamous cell carcinoma Standard excision, Mohs micrographic surgery, Curettage and electrodesiccation, Cryosurgery Imiquimoid, Diclofenac gel (3%), 5-Fluorouracil, Cetuximab PDT Radiotherapy
Melanoma Surgical excision, sentinel lymph node biopsy Imiquimod BRAF kinase Inhibitors-vemurafenib and dabrafenib, encorfenib; NRAS Inhibitors- Binimetinib; cKIT Inhibitors- imitinib and nilotinib and MEK Inhibitors—trametinib and cobimetinib. Immunotherapies for melanoma include Cytotoxic T-lymphocyte Antigen 4 Inhibitors—Ipilimumab; Programmed Cell Death Receptor 1 Inhibitors—Pembrolizumab and Nivolumab and anti-PDL1 (programmed death ligand 1)-Atezolizumab. If these fail Temozolomide and Dacarbazine Radiation therapy