Table 1 Composition of different formulations of MFH pellets
Ingredients | A1 | A2 | A3 | A4 | A5 | A6 | A7 | A8 | A9 |
|---|---|---|---|---|---|---|---|---|---|
Metformin Hydrochloride (mg) | 500 | 500 | 500 | 500 | 500 | 500 | 500 | 500 | 500 |
Carbopol 971P (mg) | 250 | 125 | 125 | 125 | 250 | 375 | 250 | 375 | 375 |
Sodium citrate (mg) | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 |
Citric acid (mg) | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 | 0.75 |
Microcrystalline cellulose (Avicel PH 101) (mg) | 342.25 | 248.5 | 342.25 | 436.0 | 248.5 | 436.0 | 436.0 | 248.5 | 373.5 |
Isopropyl alcohol (mL) | 54.375 | 52.50 | 54.375 | 56.25 | 52.50 | 56.25 | 56.25 | 52.50 | 54.375 |
Purified water (mL) | 18.125 | 17.50 | 18.125 | 18.75 | 17.50 | 18.75 | 18.75 | 17.50 | 18.125 |