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Table 3 Results of isothermal stress testing of pure drug and drug excipient mixture after 3 weeks of storage

From: Pharmacoscintigraphic evaluation and antidiabetic efficacy of gliclazide-loaded 99mTc-labelled mucoadhesive microspheres

Sample

Ratio (drug: excipients)

Quality unchanged (%w/w) *

Wavelength maxima (λ max)

Control

Stressed

Control

Stressed

GLZ (pure)

100.55 ± 0.089

99.42 ± 0.170

227

227

GLZ + sodium alginate

2:2

100.37 ± 0.251

99.29 ± 0.266

227

227

GLZ + MSB starch

2:2

100.44 ± 0.060

99.31 ± 0.077

227

227

  1. *Mean ± S.D (n = 3)
  2. GLZ: Gliclazide; MSB: Musa balbisiana starch