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Table 2 The average levels of the participants characteristics after one year of treatment

From: Optimization of osteoporosis and osteopenia management among renal transplant recipients

Parameter (reference)

Denosumab

(n = 52)

Ibandronate

(n = 48)

P-value

Vitamin D (75–250 nmol/L)

62.2 (± 6.2)

56 (± 7.1)

0.15a

Calcium (2.2–2.5 mmol/L)

2.30 (± 0.15)

2.33 (± 0.16)

0.67a

Phosphorous (0.8–1.5 mmol/L)

1.19 (± 0.14)

1.17 (± 0.19)

0.69a

Serum creatinine (40–115 µmol/L)

107.3 (± 25.5)

109.2 (± 26.3)

0.68a

Urea (2.5–6.4 mmol/L)

6.1 (± 2.3)

5.55 (± 2.62)

0.18a

Sodium (135–145 mmol/L)

138.52 (± 3.4)

138.7 (± 3.9)

0.69a

Chloride (98–107 mmol/L)

103.5 (± 3.1)

103.6 (± 3.31)

0.79a

Uric acid (208–425 µmol/L)

343.81 (± 75)

351.68 (± 69)

0.31a

Reported side effects

 Injection site reaction

10 (20%)

0

 Stomach upset

0

11 (22.9%)

0.001b

 Abdominal pain

8 (15.4%)

9 (18.75%)

0.65a

 Diarrhea and vomiting

5 (9.6%)

15 (31.25%)

0.006b

 Hypocalcaemia

6 (11.5%)

1 (2.1%)

0.037b

 Fractures

0

0

 Acute rejection

0

0

  1. Data are presented after one year of treatment as number only, mean ± standard deviation, or percentages only
  2. Categorical data are presented as percentages and were compared using the chi-squared test, while the Student T-test was used for normally distributed variables; significance was found at P ≤ 0.05
  3. aNonsignificant difference between the two groups. b Significant difference between the two groups