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Table 5 Results of robustness of Bempedoic acid and Ezetimibe

From: Characterization of novel stress degradation products of Bempedoic acid and Ezetimibe using UPLC–MS/MS: development and validation of stability-indicating UPLC method

Change in parameter

%RSD of Bempedoic acid

%RSD of Ezetimibe

Flow (0.8 ml/min)

1.24

1.22

Flow (1.2 ml/min)

0.84

0.79

Org Phase (45:55)

1.36

1.65

Org Phase (55:45)

0.97

0.77

Wavelength (225 nm)

0.82

0.85

Wavelength (235 nm)

0.79

0.81