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Table 5 Results of robustness of Bempedoic acid and Ezetimibe

From: Characterization of novel stress degradation products of Bempedoic acid and Ezetimibe using UPLC–MS/MS: development and validation of stability-indicating UPLC method

Change in parameter %RSD of Bempedoic acid %RSD of Ezetimibe
Flow (0.8 ml/min) 1.24 1.22
Flow (1.2 ml/min) 0.84 0.79
Org Phase (45:55) 1.36 1.65
Org Phase (55:45) 0.97 0.77
Wavelength (225 nm) 0.82 0.85
Wavelength (235 nm) 0.79 0.81