Table 1 Antibacterial activity of steroidal hydrazones
From: Synthesis and in vitro antimicrobial activity of new steroidal hydrazone derivatives
Compounds | E. coli | P. aeruginosa | S. aureus | S. pyogenus |
|---|---|---|---|---|
MTCC 443 | MTCC 1688 | MTCC 96 | MTCC 442 | |
MIC (minimal inhibition concentration) μmol | ||||
3 | 580 | 1159 | 232 | 1345 |
6 | 219 | 110 | 549 | 55 |
7 | 145 | 231 | 289 | 1159 |
10 | 116 | 582 | 116 | 582 |
11 | 272 | 142 | 544 | 217 |
18 | 568 | 284 | 227 | 1137 |
Gentamycin | 0.1 | 2 | 0.5 | 1 |
Ampicillin | 286 | 286 | 715 | 286 |
Chloramphenicol | 154 | 154 | 154 | 154 |
Ciprofloxacin | 75 | 75 | 150 | 150 |
Norfloxacin | 31 | 31 | 31 | 31 |