Analytical quality by design approach to RP-HPLC method development and validation for simultaneous estimation of esomeprazole and naproxen in modified-release dosage form

Future Journal of Pharmaceutical Sciences

Table 4 Data of accuracy with placebo for recovery analysis for NAP

The concentration of sample with placebo μg/ml		Peak area of NAP		Recovered Concentration μg/ml		% Recovery
Individual	Average	Sample	Standard	Individual	Average	% Recovery
200.11	200.16	1,124,221	1,407,448 (250.40 μg/ml)	200.01	200.35	99.95
200.21		1,128,894		200.84		100.32
200.15		1,125,319		200.21		100.03
249.90	249.96	1,404,567		249.89	249.92	99.99
250.03		1,404,970		249.96		99.97
249.95		1,404,707		249.91		99.98
300.51	300.33	1,698,949		302.26	301.94	100.58
300.34		1,698,704		302.22		100.63
300.15		1,693,779		301.34		100.40