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Table 8 Data for solution stability analysis

From: Analytical quality by design approach to RP-HPLC method development and validation for simultaneous estimation of esomeprazole and naproxen in modified-release dosage form

Time interval (h)

ESP solution stability

NAP solution stability

Standard

Sample

Standard

 

Sample

 

Peak area

% Difference

Peak area

% Difference

Peak area

% Difference

Peak area

% Difference

0

89,641

89,657

1,404,970

1,404,785

12

89,568

 − 0.08

89,658

0.00

1,404,785

 − 0.01

1,404,797

0.00

24

88,782

 − 0.88

89,609

 − 0.05

1,404,112

 − 0.05

1,404,757

0.00

36

86,654

 − 2.40

86,152

 − 3.86

1,403,866

 − 0.02

1,404,518

 − 0.02