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Table 1 Specificity and Selectivity data

From: Quantification of organic volatile impurities in Oseltamivir phosphate drug substances by head space gas chromatography

S. No

Name

Retention times of each solvent

Retention times of solvents in selectivity solution

Resolution between solvent peaks in selectivity solution

1

Methanol

11.61

11.62

2

Ethanol

15.55

15.55

10.9

3

Acetonitrile

16.7

16.7

3.8

4

IPA

18.31

18.32

5.5

5

DCM

21.15

21.15

10.1

6

MTBE

25.2

25.19

12.4

7

Hexane-1

25.79

25.79

1.6

8

Hexane-2

27.41

27.4

4.1

9

Ethyl acetate

28.68

28.68

3.6

10

Hexane-3

29.14

29.14

1.4

11

THF

31.12

31.12

6.3

12

Hexane-4

32.56

32.56

4.7

13

1,4-Dioxane

37.99

37.99

19.7

14

DMF

42.33

42.33

19.3

15

Toluene

43.85

43.85

7.3