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Table 1 Intra- and Inter-day accuracy and precision results for ELX and RFX

From: Validation of the HPLC–PDA method for detection of eluxadoline and rifaximin in rat plasma and application in a pharmacokinetic study

Analytes Concentration level (ng mL−1) Intra-day (n = 6) Inter-day (n = 18)
Mean found conc. (ng mL−1) CV (%) Accuracy (%) Mean found conc. (ng mL−1) CV (%) Accuracy (%)
ELX LLOQ (5.0) 5.02 ± 0.023 0.465 99.17 5.04 ± 0.036 0.717 99.6
LQC (50.0) 50.19 ± 0.207 0.413 99.65 50.43 ± 0.50 1.00 100.13
MQC (100.0) 99.89 ± 0.134 0.134 99.72 99.78 ± 0.143 0.144 99.6
HQC (150.0) 149.91 ± 0.311 0.207 99.68 149.94 ± 0.637 0.425 99.71
RFX LLOQ (10.0) 10.19 ± 0.138 1.358 99.42 10.18 ± 0.12 1.186 99.39
LQC (100.0) 100.36 ± 0.148 0.147 100.2 100.42 ± 0.131 0.130 100.2
MQC (200.0) 200.21 ± 0.077 0.038 100.0 200.23 ± 0.143 0.071 100.0
HQC (300.0) 302.16 ± 2.457 0.813 100.16 300.16 ± 2.157 0.714 100.61