Skip to main content

Table 5 Univariate logistic regression analysis for factors associated with in-hospital mortality

From: Mortality and its predictors among hospitalized patients with infections due to extended spectrum beta-lactamase (ESBL) Enterobacteriaceae in Malaysia: a retrospective observational study

Variable Odds ratio 95% Confidence Interval P value
Age 1.02 0.97–1.06 0.382
Female gender 0.58 0.19–1.74 0.334
Race
Malay Reference  
Chinese 1.92 0.00– 0.581
Indian 1.82 0.00– 0.999
Others 1.46 0.00– 0.999
Intensive care unit admission 11.57 3.43–38.96  < 0.001
Active empiric antibiotics 1.11 0.39–3.18 0.838
Immunocompromised 1.55 0.44–5.45 0.490
Sepsis/septic shock 17.87 2.24–142.27 0.006
Type of infection 1.97 0.65–5.99 0.229
Pathogen
K. pneumoniae Reference  
E. coli 1.36 0.44–4.22 0.586
Others 1.48 0.15–14.63 0.734
Diabetes mellitus 3.40 1.01–11.46 0.048
Hypertension 1.68 0.53–5.31 0.372
Chronic kidney disease 2.17 0.71–6.57 0.170
Malignancy 1.64 0.46–5.80 0.437
Empiric piperacillin–tazobactam therapy 5.62 1.79–17.67 0.003
Empiric beta-lactam beta-lactamase inhibitor 2.35 0.77–7.15 0.132
Empiric meropenem 0.54 0.06–4.56 0.576
Empiric carbapenem 0.45 0.05–3.72 0.459
Days to active antibiotic therapy 1.00 0.99–1.00 0.308
Hemodynamic support 28.00 2.17–361.21 0.011
Fever 1.59 0.46–5.46 0.457
Leucocytosis 6.65 0.83–53.08 0.074
Tachycardia 0.91 0.29–2.82 0.882
Tachypnea 4.09 0.67–24.97 0.127
Elevated serum creatinine 7.86 1.68–36.75 0.009
Elevated serum urea 2.04 0.64–6.42 0.222
Anemia 2.44 0.51–11.60 0.259
Thrombocytopenia 4.20 1.28–13.78 0.018
Hypoalbuminemia 4.44 1.17–16.76 0.028
Hyperbilirubinemia 5.09 1.51–17.05 0.008
Polymicrobial infections 0.65 0.13–3.17 0.603
Lowest systolic blood pressure 0.98 0.95–1.01 0.432
Lowest diastolic blood pressure 0.99 0.95–1.04 0.840
Bacteremia 1.64 0.55–4.89 0.375
Pneumonia 11.15 2.20–56.47 0.004
Urinary tract infection 0.11 0.01–0.88 0.038
Skin and soft tissue infections 0.82 0.16–4.01 0.807
Transaminitis 4.69 1.51–14.60 0.008
  1. Bold font in the tables denotes statistical significance