Table 5 Univariate logistic regression analysis for factors associated with in-hospital mortality

Age

1.02

0.97–1.06

Female gender

0.58

0.19–1.74

Race

Malay

Reference

–

Chinese

1.92

0.00–

Indian

1.82

0.00–

Others

1.46

0.00–

Intensive care unit admission

11.57

3.43–38.96

Active empiric antibiotics

1.11

0.39–3.18

Immunocompromised

1.55

0.44–5.45

Sepsis/septic shock

17.87

2.24–142.27

Type of infection

1.97

0.65–5.99

Pathogen

K. pneumoniae

Reference

–

E. coli

1.36

0.44–4.22

Others

1.48

0.15–14.63

Diabetes mellitus

3.40

1.01–11.46

Hypertension

1.68

0.53–5.31

Chronic kidney disease

2.17

0.71–6.57

Malignancy

1.64

0.46–5.80

Empiric piperacillin–tazobactam therapy

5.62

1.79–17.67

Empiric beta-lactam beta-lactamase inhibitor

2.35

0.77–7.15

Empiric meropenem

0.54

0.06–4.56

Empiric carbapenem

0.45

0.05–3.72

Days to active antibiotic therapy

1.00

0.99–1.00

Hemodynamic support

28.00

2.17–361.21

Fever

1.59

0.46–5.46

Leucocytosis

6.65

0.83–53.08

Tachycardia

0.91

0.29–2.82

Tachypnea

4.09

0.67–24.97

Elevated serum creatinine

7.86

1.68–36.75

Elevated serum urea

2.04

0.64–6.42

Anemia

2.44

0.51–11.60

Thrombocytopenia

4.20

1.28–13.78

Hypoalbuminemia

4.44

1.17–16.76

Hyperbilirubinemia

5.09

1.51–17.05

Polymicrobial infections

0.65

0.13–3.17

Lowest systolic blood pressure

0.98

0.95–1.01

Lowest diastolic blood pressure

0.99

0.95–1.04

Bacteremia

1.64

0.55–4.89

Pneumonia

11.15

2.20–56.47

Urinary tract infection

0.11

0.01–0.88

Skin and soft tissue infections

0.82

0.16–4.01

Transaminitis

4.69

1.51–14.60