Fig. 3

Histopathology of the liver from control rat (a) showed normal architecture of hepatocytes. HFHF diet rats (b, c) caused liver steatosis (black arrows), hepatocytes ballooning (b), green square boxes indicate immune cell infiltration, yellow circles indicate binuclear hepatocytes, black circles show that glycogenated nuclei are mainly located in the area surrounding the portal tract, and Kupffer cells (blue arrows). Silymarin-treated HFHF-challenged rat (d) showed normal hepatocytes but immune cell infiltration (green square) is seen, curcumin-treated HFHF-challenged rat showed hepatic sinusoidal dilatation (red arrows), (e) and celery-treated HFHF-challenged rat (f) normal architecture almost similar to control