Fig. 5

Images from the ebselen plaque-reduction assay. With respect to the negative control (NC) and the positive control (PC), the number of plaques decreases as the concentration of ebselen increases DMSO. The results are a composite of four biological replicates. The drug’s antimicrobial properties against SARS-CoV-2. a qRT-PCR analysis was used to estimate the number of absolute viral RNA (vRNA) copies (per ml) in the supernatant 72 h after infection. The data represent the mean s.e.m. of three biological replicates, ebselen dose–response curves, and b N3, c plaque-reduction assay. All data are presented as mean s.e.m., based on four biological replicates