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Table 4 Process-controlled parameters optimization by trial-and-error method

From: Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid

Batch no

Boswellic acid (mg)

Conc. Of tween 80 (%)

FFT (℃)

HT (ºc)

H time (minutes)

%EE

BA 1

300

0.75

40

70

90

88.81 ± 0.533

BA 2

300

0.75

45

70

90

92.10 ± 0.511

BA 3

300

0.75

50

70

90

85.30 ± 0.236

BA 4

300

0.75

45

60

90

84.60 ± 0.482

BA 5

300

0.75

45

70

90

90.89 ± 0.623

BA 6

300

0.75

45

80

90

86.57 ± 0.319

BA 7

300

0.75

45

70

60

81.93 ± 0.587

BA 8

300

0.75

45

70

90

86.70 ± 0.498

BA 9

300

0.75

45

70

120

86.07 ± 0.617

  1. The bold digit in column 4, 5 and 6 differentiate the condition while bold digit in last column indicate based on that result process parameters were selected
  2. (Mean ± SD, where n = 3)