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Table 5 Formulation parameters optimization by 32 full factorial design

From: Development and evaluation of ultradeformable vesicles loaded transdermal film of boswellic acid

Batch no. Amount of lecithin (X1) (mg) Concentration of surfactant (X2) (%) Vesicle size (Y1) (nm) Drug EE(Y2) (%)
BA 10 150 0.5 247.9 ± 0.219 86.68 ± 0.553
BA 11 200 0.5 283.6 ± 0.355 91.17 ± 0.267
BA 12 250 0.5 317.7 ± 0.314 95.63 ± 0.392
BA 13 150 0.75 193.5 ± 0.268 85.57 ± 0.561
BA 14 200 0.75 266.3 ± 0.347 90.52 ± 1.133
BA 15 250 0.75 305.8 ± 0.532 92.85 ± 0.619
BA 16 150 1 187.5 ± 1.122 82.72 ± 0.546
BA 17 200 1 242.9 ± 0.598 88.25 ± 0.367
BA 18 250 1 300.8 ± 0.361 96.92 ± 0.466
  1. (Mean ± SD, where n = 3)