Skip to main content
Future Journal of Pharmaceutical Sciences
Fig. 7 | Future Journal of Pharmaceutical Sciences

Fig. 7

From: Exploring Clinacanthus nutans leaf different solvent extracts on antiproliferative effects induced metastasis through apoptosis and cell cycle against MCF-7 human breast cancer cell lines

Fig. 7

Dot plots for flow cytometry analysis of the apoptosis effects MCF-7 cells treated with IC50 CNDCM for 72 h. MCF-7 cells were exposed to vehicle control, IC50 CNDCM and positive control. A Dot plots and B histogram for apoptosis analysis. A Quadrant location for the representative dot plots: UL (upper left)—FITC−/PT+ (necrotic cells); UR (upper right)—FITC+/PI+ (late apoptotic cells); LL (lower left)—FITC−/PI− (viable cells); LR (lower right)—FITC+/PI− (early apoptotic cells). B Percentage of cell distribution of MCF-7 cells as determined by annexin V-FITC and PI staining. Asterisks signify significance statistically at p < 0.05 compared to control (untreated MCF-7 cells) and positive control (4-OH-TAM). The percentage of the MCF-7 cell population was increased significantly for both IC50 of CNDCM extracts and positive control of treatment when compared with the control group

Back to article page