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Table 3 Effect of N. canescens Extracts and fractions on the Lipid Profile (mg/dL) of Alloxan-induced Diabetic Rats

From: Nelsonia canescens (Acanthaceae) aqueous extract and partitioned fractions ameliorates type-2 diabetes in alloxan-induced diabetic rats

Lipid Profiles

AQ 50

AQ 300

EA 50

EA 300

ME 50

ME 300

Glibenclamide

Diabetic control

Normal control

Total cholesterol

349.17 ± 34.54a

338.06 ± 4.44a

423.89 ± 56.39b

474.17 ± 59.84b

650.28 ± 0.00c

438.89 ± 60.83b

357.87 ± 37.73a

835.28 ± 27.22d

471.39 ± 55.45b

HDL-Cholesterol

281.33 ± 69.37a

354.00 ± 46.50b

128.50 ± 39.00a

512.63 ± 115.02d

1315.00 ± 0.00e

507.50 ± 5.00d

326.83 ± 63.42b

1414.25 ± 9.25e

500.75 ± 100.72d

LDL-Cholesterol

48.54 ± 37.09a

31.68 ± 25.69a

74.66 ± 18.91b

107.38 ± 36.10c

36.51 ± 0.00a

96.24 ± 58.76c

78.70 ± 16.43b

251.34 ± 39.01e

148.39 ± 43.55d

Triacylglycerol

244.36 ± 19.82a

235.58 ± 20.83a

323.5 ± 89.68b

264.26 ± 21.71ab

350.77 ± 0.00b

241.15 ± 3.08a

213.80 ± 11.51a

301.09 ± 9.94b

222.85 ± 15.38a

  1. Values are expressed in men ± standard error of mean; n = 5. Values with the same superscript on the same row have no significant difference (p < 0.05)
  2. Key: AQ = Aqueous extract, EA = Ethylacetate fraction, ME = Methanol fractions