Table 3 Per protocol analysis results of the primary and secondary outcomes (N = 84)

Mean gestational age at delivery (weeks)

All gravidae

39.06 ± 1.59

39.63 ± 1.30

^–

Primigravidae

39.36 ± 0.81

39.67 ± 1.09

^–

Multigravidae

38.92 ± 1.82

39.60 ± 1.43

^–

Rogerson placental malaria category

None

All gravidae

17 (47.2)

21 (43.8)

1.08 (0.66–1.77)

Acute

All gravidae

0 (0.0)

4 (8.3)

–

Chronic

All gravidae

5 (13.9)

13 (27.1)

1.69 (0.77–3.72)

Past

All gravidae

14 (38.9)

10 (20.8)

0.63 (0.39–1.01)

Placental malaria

All gravidae

19 (52.8)

27 (56.2)

1.08 (0.66–1.77)

Primigravidae

5 (45.5)

10 (55.6)

1.29 (0.50–3.28)

Multigravidae

14 (56.0)

17 (56.7)

1.02 (0.57–1.82)

Stillbirth

All gravidae

0 (0.0)

0 (0.0)

–

Primigravidae

0 (0.0)

0 (0.0)

–

Multigravidae

0 (0.0)

0 (0.0)

–

Low birth weight

All gravidae

5 (13.9)

3 (6.2)

0.65 (0.36–1.19)

Primigravidae

0 (0.0)

1 (5.6)

–

Multigravidae

5 (20.0)

2 (6.7)

0.58 (0.33–1.04)

Preterm delivery

All gravidae

2 (5.6)

1 (2.1)

0.63 (0.27–1.46)

Primigravidae

0 (0.0)

0 (0.0)

–

Multigravidae

2 (8.0)

1 (3.3)

0.66 (0.28–1.56)

Small for gestational age

All gravidae

2 (5.6)

1 (2.1)

0.63 (0.27–1.46)

Primigravidae

0 (0.0)

0 (0.0)

–

Multigravidae

2 (8.0)

1 (3.3)

0.66 (0.28–1.56)

Congenital malformation

All gravidae

0 (0.0)

0 (0.0)

–

Primigravidae

0 (0.0)

0 (0.0)

–

Multigravidae

0 (0.0)

0 (0.0)

–

Low APGAR score

All gravidae

2 (5.6)

0 (0.0)

0.42 (0.32–0.52)

Primigravidae

0 (0.0)

0 (0.0)

–

Multigravidae

2 (8.0)

0 (0.0)

0.43 (0.32–0.59)

Composite adverse birth outcome^#

All gravidae

5 (13.9)

3 (6.2)

0.65 (0.36–1.19)

Primigravidae

0 (0.0)

1 (5.6)

–

Multigravidae

5 (20.0)

2 (6.7)

0.58 (0.33–1.04)