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Future Journal of Pharmaceutical Sciences

Table 7 Percent growth inhibition at different concentrations of SN-38, IHCl, drug loaded nanoparticles at various concentrations for HT-29 cell line

From: Targeting efficacy and anticancer activity of polymeric nanoparticles of SN-38 on colon cancer cell lines

Drugs/formulation

Concentration µM

10–3

10–2

10–1

1

SN-38

67.4 ± 3.6

49.6 ± 4.1

36.7 ± 2.9

21.5 ± 2.6

I Hcl

93.6 ± 3.8

84.6 ± 3.9

75.8 ± 2.8

69.5 ± 2.4

CsENP

72.3 ± 4.2

57.8 ± 3.5

45.8 ± 2.1

28.7 ± 4.1

Adriamycin

10.6 ± 0.1

2.3 ± 0.24

0.6 ± 0.02

− 1.6 ± 0.04

  1. The values represent mean ± S.D (n = 3)
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